[Of all the things Itachi was expecting as potential responses, that wasn't anywhere on the list. This unknown kunoichi sounds... well, casual about his presence, which would make sense if the knowledge of what he's done has been somehow suppressed. But she also sounds like she knows him, and he's quite certain he's never met her before. And even if she doesn't sound like someone talking to a familicidal mass murderer, she doesn't sound terribly happy to see him, either. Or look it.
no subject
Besides, again?]
... I'm sorry, do I know you?